Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells.
By H. Koenen, R. Smeets, P. Vink, Esther van Rijssen, A. Boots, I. Joosten. Blood, 2008
793 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/722fd7e2d7f42f783a1b690f60a1164278ee1205
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In Immunology
Citations in the corpus
- Plasticity of CD4+ T cell lineage differentiation. (2009, result): “These findings suggest an intimate link between the Treg and Th17 cell programs of differentiation, and indeed there is evidence for such a relationship from both in vitro and in vivo studies (Bettelli et al., 2006; Zhou et al., 2008a; Yang et al., 2008a; Koenen et al., 2008; Beriou et al., 2009).”
- A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease (2019, background): “Recent data have documented that memory Treg can convert into Th17 cells under inflammatory conditions, in which IL-1 is the key molecule in promoting conversion [192, 193].”