Guidance of primordial germ cell migration by the chemokine SDF-1.

By M. Doitsidou, M. Reichman-Fried, Jürg Stebler, Marion Köprunner, Julia Dörries, D. Meyer, Camila V. Esguerra, TinChung Leung, E. Raz. Cell, 2002

700 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/718fd0b55d4e37b68ed930e916f05936f2aceb77

How researchers see this paper

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In Immunology

1. A. Zlotnik
2. O. Yoshie
3. J. Zambonino-Infante
4. Heiko Blaser
5. Jianhua Wang
6. M. Yúfera

In Molecular Biology

1. J. Zambonino-Infante
2. J. Postlethwait
3. Jianhua Wang
4. I. Braasch
5. M. Felici
6. R. Taichman

Citations in the corpus

• The chemokine and chemokine receptor superfamilies and their molecular evolution (2006, background): “Two groups have reported that, in the zebrafish, the CXCL12-CXCR4 pair regulates the homing of primordial germ cells to the gonads, where they differentiate into gametes [19,20].”
• Control of chemokine-guided cell migration by ligand sequestration. (2008, methodology): “Knockdown of CXCR4b and both zebrafish SDF-1 homologs was achieved using 0.4 pmol of either oligonucleotides against cxcr4b, sdf-1a (Doitsidou et al., 2002), and sdf-1b (50-TTGCTATCCATGCCAAGAGCG AGTG-30).”
• Polyploidy in Fish and the Teleost Genome Duplication (2012, background): “Zebrafish has co-orthologs of Cxcl12 that appear to have arisen in the TGD (Doitsidou et al. 2002).”
• Origin, Migration, and Proliferation of Human Primordial Germ Cells (2013, background): “The tumor growth factorb (TGF b ) [ 92 ] , stromal-derived factor1 (SDF1) [ 93 ] , and stem cell factor (SCF, or c-Kit ligand, KL) [ 91 ] have been proposed as chemoattractants for mouse PGCs.”
• The Chemokine Superfamily Revisited (2012, unknown): “One of the most useful experimental models to understand these mechanisms has been the zebrafish, where CXCR4 is the signal that guides stem cells that give rise to the gonads of the developing fish embryo (Doitsidou et al., 2002; Knaut et al., 2003).”
• CXCL12/CXCR4/CXCR7 Chemokine Axis and Cancer Progression (2010, background): “For example, the deficiency of this axis leads to circulatory, CNS, immune, and hematopoietic defects [36, 37].”
• Fantastically plastic: fish larvae equipped for a new world (2013, background): “Migration of PGCs towards the germinal ridge is guided by stromal-cellderived factor-1a which acts through its G-protein-coupled receptor, CXCR4b (Doitsidou et al. 2002; Blaser et al. 2006).”