The case for post-predictional modifications in the AlphaFold Protein Structure Database

By Haroldas Bagdonas, Carl A. Fogarty, Elisa Fadda, J. Agirre. 2021

68 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. Anastassis Perrakis
2. Robbie P. Joosten
3. T. Croll
4. G. Murshudov

In Molecular Biology

1. Anastassis Perrakis
2. Robbie P. Joosten
3. I. de Vries
4. Maarten L. Hekkelman
5. T. Croll
6. G. Murshudov

Citations in the corpus

• Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom (2023, neutral): “Many essential protein functions, such as receptor signaling, immune evasion, and enzyme activity, involve covalent modifications of amino acid side chains with sugars, phosphates, lipids, andother molecules ( 34 – 37 ).”
• AlphaFill: enriching AlphaFold models with ligands and cofactors (2022, background): “It also does not handle posttranslational modifications and, in particular, glycosylation, which is a complicated matter that requires special attention 31 .”