Structural Basis of Transcription Initiation: An RNA Polymerase Holoenzyme-DNA Complex

By K. Murakami, S. Masuda, E. Campbell, Oriana Muzzin, S. Darst. Science, 2002

669 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Catabolite activator protein: DNA binding and transcription activation. (2004, methodology): “Models were constructed by: (i) joining crystal structures of the CAP–aCTD–DNA complex (PDB code 1LB2 [44 ]), the sR4–( 35 element) complex (PDB code 1KU7 [47 ]), and an RNAP–DNA complex (PDB code 1L9Z [49 ]; residues 150–160 and 164–170 of aNTD modeled as in PDB entry 1BDF [65]; residues 161–163 of”
The regulation of bacterial transcription initiation (2004, background): “Although domains 2, 3 and 4 are known to be involved in promoter recognitio”
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex (2009, methodology): “The published model was constructed based on the crystal structure of the CAP- CTD-DNA complex (8) and the crystal structure of an RNAP-DNA complex (37), using restraints derived from genetic and biochemical experiments defining protein-protein contacts (2).”