Differential aging of the brain: patterns, cognitive correlates and modifiers.

By Naftali Raz, Karen M. Rodrigue. Neuroscience and Biobehavioral Reviews, 2006

1,211 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/7014a930f1b842ab8c858313fa51e81691dcb9a0

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Citations in the corpus

Effects of memory training on cortical thickness in the elderly (2010, background): “, 2009, in press-a,b) and functional decline across multiple cognitive domains (Mahncke et al., 2006; Raz and Rodrigue, 2006).”
One year brain atrophy evident in healthy aging (2009, background): “…imaging (MRI) studies have demonstrated consistent age-effects (Raz et al., 2004; Salat et al., 2004; Allen et al., 2005; Walhovd et al., 2005; Raz and Rodrigue, 2006; Fjell et al., 2009a,b; Westlye et al., 2009), longitudinal MR studies have often been limited by relatively small numbers of…”
Predicting brain-age from multimodal imaging data captures cognitive impairment (2016, positive): “Establishing the trajectories of such changes over the lifespan provides a basis for characterizing clinically-relevant deviations (Ziegler et al., 2012; Raz & Rodrigue, 2006).”
High consistency of regional cortical thinning in aging across multiple samples. (2009, background): “Cerebral Cortex September 2009;19:2001--2012 doi:10.1093/cercor/bhn232 Advance Access publication January 15, 2009”
Social and Emotional Aging (2010, background): “In contrast, the prefrontal cortex shows the most dramatic age differences, characterized by age-related increases until the mid-twenties, a plateau with very small rates of decline until the mid-fifties, and then an accelerated decline in later life (Raz & Rodrigue 2006).”
Brain Age from the Electroencephalogram of Sleep (2018, background): “From the organ-systems level, brain anatomy changes dramatically throughout life (Raz and Rodrigue, 2006).”
Decreased Functional Connectivity by Aging Is Associated with Cognitive Decline (2012, background): “Structural neuroimaging studies including voxel-based morphometry and diffusion tensor imaging indicate that the gray matter of the human brain selectively shrinks with age and that this shrinkage is associated with the selective disruption of anatomical connections (Raz & Rodrigue, 2006 ).”
Source monitoring 15 years later: What have we learned from fMRI about the neural mechanisms of source memory? (2009, background): “Aging disproportionately affects the PFC, compared with other brain regions (Raz & Rodrigue, 2006), and these structural and functional changes also have been associated with cognitive dysfunction, though again, the relationships are far from perfect (see, e.g., Dennis & Cabeza, 2008; Raz &…”
Models of the Aging Brain Structure and Individual Decline (2012, background): “On one hand there is evidence that hypertension (Raz and Rodrigue, 2006), obesity and diabetes (Luchsinger and Gustafson, 2009), and high plasma homocysteine concentrations (Oulhaj et al.”
Decreased segregation of brain systems across the healthy adult lifespan (2014, background): “Although this may be an adaptive response to ongoing anatomical and biochemical alterations (1, 2), it does not appear that the increasing interaction between areas in distinct systems confers a benefit to the individual; rather, the increased “blurring” across systems and decreased communication wi”
Age-related differences in white matter microstructure: Region-specific patterns of diffusivity (2010, background): “The human brain displays significant structural and functional changes across adulthood (Raz and Rodrigue, 2006).”
Structural Brain Changes in Aging: Courses, Causes and Cognitive Consequences (2010, result): “Course Not related to age Effects Eleven studies found reductions in total cerebellar volume, cerebellar GM, cerebella WM, or other cerebellar compartments [24, 32, 48, 52, 62, 64, 66, 69-72], one study found η effects on cerebellar WM [70], in contrast to a more recent study [73], one study observe”
Age-Related Characteristics of Resting-State Electroencephalographic Signals and the Corresponding Analytic Approaches: A Review (2024, background): “In brief, aging is known to mediate the morphology of neurons and synaptic plasticity differentially in the hippocampus and cerebral cortex [10,11].”