Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk

By Walter C. Willett, MR Stampfer, Frank M. Sacks. Annals of Internal Medicine, 2014

858 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Omega-6 FAs such as arachidonic acid are primarily pro-inflammatory [75,131,132], constituting precursors of several pro-inflammatory mediators including eicosanoids (a subset of oxylipins) such as prostaglandins and leukotrienes derived from cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, resp”
Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective (2015, result): “Until recently, meta-analyses were also largely positive although there have been some recent studies showing less effect (Rizos et al., 2012; Chowdhury et al., 2014).”
Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021 (2021, background): “Clearly, there is substantial 551 evidence that omega-3 PUFAs, especially EPA and DHA) reduce risk of CVDs especially 552 CHD [178], acting through plausible mechanisms of action to beneficially affect a range of 553 risk factors [145].”
Fatty Acids Composition of Vegetable Oils and Its Contribution to Dietary Energy Intake and Dependence of Cardiovascular Mortality on Dietary Intake of Fatty Acids (2015, background): “mortality and do not clearly support cardiovascular guidelines promoting high consumption of n-6 PUFAs and suggest reduced consumption of SFAs [63,64].”