The SWI/SNF complex and cancer

By D. Reisman, Selina Glaros, E. Thompson. Oncogene, 2009

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Epigenetic antagonism between Polycomb and SWI/SNF complexes during oncogenic transformation (2010, unknown): “…evidence raises the possibility that SWI/SNF complexes have a more widespread role in preventing tumorigenesis as specific mutations of this complex have been identified in cancers of the lung, breast, prostate, and pancreas (Roberts and Orkin, 2004; Medina et al., 2008; Reisman et al., 2009).”
Cancer Genetics and Epigenetics: Two Sides of the Same Coin? (2012, background): “SWI/SNF complexes remodel chromatin by changing nucleosome occupancy pattern, thereby contributing to either transcriptional activation or repression (Reisman et al., 2009; Wilson and Roberts, 2011).”
Epigenetics in cancer. (2010, background): “However, such treatment also resulted in acetylation of BRM protein which abrogated its function [104].”
Epigenetic modifications and human disease (2010, background): “Moreover, SWI/SNF has also been reported to modulate alternative splicin”