The developmental role of serotonin: news from mouse molecular genetics

By P. Gaspar, O. Cases, L. Maroteaux. Nature Reviews Neuroscience, 2003

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5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression (2005, background): “Furthermore, serotonin (5-HT) appears to be critical for the development of emotional circuitry in the brain, and even transient alterations in 5-HT homeostasis during early development modify neural connections implicated in mood disorders and cause permanent elevations in anxiety-related behaviors”
Interaction between BDNF and Serotonin: Role in Mood Disorders (2008, background): “In addition to its prominent role as a neurotransmitter, 5-HT plays an important role in brain development via regulation of neurite outgrowth, synaptogenesis, and cell survival (”
Critical periods in speech perception: new directions. (2015, background): “Developing circuits transiently express ectopic serotonergic receptors and transporters (Gaspar et al. 2003).”
Serotonin modulates circadian entrainment in Drosophila. (2005, background): “Serotonin has an important role in the modulation of various physiological functions and complex behaviors such as locomotion, learning and memory, feeding, addiction, and aggression (Buhot et al., 2000; Gaspar et al., 2003).”