Oxidative stress in normal and impaired wound repair.

By Matthias Schäfer, S. Werner. Pharmacological Research, 2008

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Therapeutic Strategies for Enhancing Angiogenesis in Wound Healing (2018, background): “Reactive oxygen species can impair stem cell function and reduce wound healing [311,312].”
Transition from inflammation to proliferation: a critical step during wound healing (2016, background): “Excessive amounts of ROS cause oxidative stress, which damage cells and are observed in chronic hard-to-heal wounds [119].”
The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults (2016, background): “Increased ROS production and increased level of the oxidative stress play role in the etiology of the superficial punctate keratopathy [58] and impair the corneal wound healing [59, 60].”
Wound repair at a glance (2009, background): “In addition to the release of cytokines and growth factors, inflammatory cells exert their influence on the surrounding tissue by generating NO and large amounts of ROS (Schafer and Werner, 2008).”