Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress.

By Constantine Tsigos, George P. Chrousos. Journal of Psychosomatic Research, 2002

2,878 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Endocrinology, Diabetes and Metabolism, Social Psychology

View Paper: https://www.semanticscholar.org/paper/6b11e5d0e59d376aa72913ae62a6ef3cde9e3752

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Citations in the corpus

Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy. (2017, background): “proinflammatory state affects glucocorticoid gene expression and function (Pariante and Miller, 2001), stimulates activity of the HPA axis (Tsigos and Chrousos, 2002), and attenuates the noradrenaline and serotonin content in the brain (Leonard, 2001) and may, thus, have an pathophysiological role i”
A Unified Model of Depression (2016, positive): “…consistent biological correlates of severe depression (see Pariante & Lightman, 2008; Stetler & Miller, 2011) and may be linked to serotonergic or noradrenergic dysfunction (given the important role of these neurotransmitters in HPA activation/regulation; see Dinan, 1996; Tsigos & Chrousos, 2002).”
Interactions between Temperament, Stress, and Immune Function in Cattle (2011, background): “An additional subset of vagal and sacral parasympathetic efferent nerves is activated which mediate the gut response to stress [30].”
Thermogenic mechanisms and their hormonal regulation. (2006, background): “CRH and products of the POMC gene will inhibit appetite and activate pathways to increase thermogenesis (235, 253), but the net effect of these signals will depend on others, such as NPY and agouti-related protein (AGRP), which in turn depend on peripheral signals, notably leptin and probably insuli”
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity (2007, background): “ACTH, in turn, stimulates the adrenal glands to release glucocorticoid”
Emotion and the Prefrontal Cortex: An Integrative Review (2017, background): “…alongside regions such as the hypothalamus and periacqueductal gray that trigger patterned physiological responses (e.g., coordinated changes in heart rate, blood pressure, hormone levels) to cope with emotionally significant events (Bandler et al., 2000; Saper, 2002; Tsigos & Chrousos, 2002).”
The brain and the stress axis: The neural correlates of cortisol regulation in response to stress (2009, background): “McEwen,1998); the fine-balanced regulation of stress-induced as well as basal cortisol secretion is thus essential for the maintenance of homeostasis (McEwen, 2000; Tsigos and Chrousos, 2002).”
Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018, background): “The vagal afferent pathways are involved in the activation/regulation of the HPA axis (29), which coordinates the adaptive responses of the organism to stressors of any kind (30).”
Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. (2009, background): “…results is surely beyond the scope of this overview and numerous reviews on this topic can be found elsewhere (Holsboer, 1989; Heuser et al., 1994a; Tsigos and Chrousos, 1994, 2002; Buske-Kirschbaum et al., 2001; Buske-Kirschbaum and Hellhammer, 2003; Burke et al., 2005; Kudielka et al., 2007c;…”