A temporally asymmetric Hebbian rule governing plasticity in the human motor cortex.

By A. Wolters, F. Sandbrink, A. Schlottmann, E. Kunesch, K. Stefan, Leonardo G. Cohen, R. Benecke, J. Classen. Journal of Neurophysiology, 2003

620 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Electrical and Electronic Engineering, Neurology

View Paper: https://www.semanticscholar.org/paper/6a04f2a6c3626d24341adfbdb37ef5bb2a94e978

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Citations in the corpus

Basic principles of transcranial magnetic stimulation (TMS) and repetitive TMS (rTMS). (2015, background): “In contrast, if ISI is longer than the afferent delay, PAS increases cortical excitability [42].”
Transcranial magnetic stimulation: a primer. (2007, positive): “As a simple motor learning task and PAS interact with each other, it does appear that PAS is a highly relevant model for brain plasticity (Ziemann et al., 2004).”
Dendritic excitability and synaptic plasticity. (2008, positive): “In the case of STDP, phenomena consistent with an in vivo role for STDP have been repeatedly been discovered, for example, in rat (24, 118, 330, 516, 678), cat (224, 232, 864), Xenopus tadpoles (201, 539, 803, 875, 876), as well as in humans (232, 846, 847, 858, 859).”
Spike timing-dependent plasticity: from synapse to perception. (2006, background): “Remarkably, plasticity resembling STDP has been demonstrated in the human motor cortex (101, 114).”
Differential Modulation of Motor Cortical Plasticity and Excitability in Early and Late Phases of Human Motor Learning (2007, methodology): “7A), the PAS protocols produced the expected effects of MEP facilitation after PAS25 and suppression after PAS10 (Stefan et al., 2000; Wolters et al., 2003).”
Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases (2014, positive): “The resulting plasticity involves glutamatergic 96 synapses, and is calcium-dependent (Nitsche et al., 2003a, 2004b; 97 Stefan et al., 2002; Wolters et al., 2003).”
Plasticity in the human central nervous system. (2006, background): “, 2000), mis-timing of peripheral and TMS stimulation, by shortening the interval between the two, results in a depression of cortical excitability lasting for an hour and a half (Wolters et al., 2003).”
Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee (2015, methodology): “This bidirectional PAS-induced plasticity is reminiscent of what is observed in experimental models of associative long-term synaptic plasticity, i.e., long-term potentiation, LTP, and long-term depression, LTD (Stefan et al., 2000, 2002; Wolters et al., 2003, 2005; Classen et al., 2004).”
Enhancement of human cognitive performance using transcranial magnetic stimulation (TMS) (2013, background): “For example, repeated co-stimulation of the median nerve in the forearm and motor cortex can potentiate subsequent MEPs evoked by TMS (Stefan et al., 2000; Wolters et al., 2003).”
The spike timing dependence of plasticity (2012, background): “In motor cortex, similar pairing bidirectionally alters the amplitude of motor-evoked potentials (Wolters et al., 2003).”
The role of interneuron networks in driving human motor cortical plasticity. (2013, result): “Rapid decline of facilitation as the MEP latency difference increases can be accounted for by the assumption that maximum STDP occurs at 3 ms in human motor cortex since previous STDP-like plasticity by PAS has relatively narrow time window compared with animal experiments (Wolters et al. 2003).”
Determinants of the induction of cortical plasticity by non‐invasive brain stimulation in healthy subjects (2010, methodology): “…the NMDAR antagonist dextromethorphan blocks the induction of LTP-like and LTD-like plasticity induced with the PAS protocol (Stefan et al. 2002; Wolters et al. 2003) as well as the LTP-like and LTD-like effects seen following both anodal and cathodal tDCS (Liebetanz et al. 2002; Nitsche et al.…”