Microglia promote the death of developing Purkinje cells.
By José L Marín-Teva, I. Dusart, C. Colin, A. Gervais, Nico van Rooijen, M. Mallat. Neuron, 2004
732 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Neurology
View Paper: https://www.semanticscholar.org/paper/695a744e6663c259c4f1170a06acd1f0159024fb
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In Cellular and Molecular Neuroscience
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In Neurology
Citations in the corpus
- The role of glia in the spinal cord in neuropathic and inflammatory pain. (2015, background): “However, rather than simply removing waste, microglia can initiate apoptosis of cells via the release of several factors including superoxide ions and TNF (Marin-Teva et al. 2004; Sedel et al. 2004; Salter and Beggs 2014).”
- Debris clearance by microglia: an essential link between degeneration and regeneration (2008, background): “death and removal by microglial cells (Marin-Teva et al., 2004).”
- Microglia promote learning-dependent synapse formation through BDNF (2013, background): “In the embryonic brain, which has high levels of programmed neuronal cell death, microglia have been observed to phagocytose apoptotic neurons (Peri and Nüsslein-Volhard, 2008) or actively participate in the killing of neurons (Marı́n-Teva et al., 2004).”
- Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis (2010, background): “During development, microglia play an essential role by phagocytosing the excess of neuroblasts, such as in the cerebellum (Marı́n-Teva et al., 2004).”
- Origin and Functions of Tissue Macrophages (2014, background): “The M1 versus M2 designation is a widely utilized paradigm in mice and appears to be conserved to some degree in humans (Martinez et al., 2013).”