Corrigendum: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

By Madeleine P. Ball, Jin Billy Li, Yuan Gao, Je-Hyuk Lee, E. Leproust, In-Hyun Park, Bin Xie, G. Daley, George M. Church. 2009

616 citations recorded by the source corpus.

Subfields: Molecular Biology

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Citations in the corpus

Impact of cytosine methylation on DNA binding specificities of human transcription factors (2017, background): “Gene bodies of highly expressed genes are heavily methylated (4, 5), whereas active gene regulatory elements have a low degree of methylation (6–8).”
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX (2014, neutral): “The impact of this technology is vast, with many applications in biosciences, including genome-wide SNP 3 and copy number variation (CNV) 4 discovery, nucleosome mapping 5 and genome-wide methylation profiling 6 , genome re-sequencing 7 and de novo genome assembly 8 .”
Neuronal activity modifies DNA methylation landscape in the adult brain (2011, background): “, emerging evidence suggests diverse roles of DNA methylation in various contexts, including promoting gene expressio”
DNA methylation: superior or subordinate in the epigenetic hierarchy? (2011, background): “However, the finding that intragenic methylation contributes to gene silencing(51) is seemingly contradictory to others’ conclusions that gene body methylation correlates with increased transcription.(2,89,95,96,100) The discrepancy may arise from the different methods of measuring DNA methylation a”
Epigenetic choreographers of neurogenesis in the adult mammalian brain (2010, methodology): “By taking advantage of next-generation sequencing technologies, researchers can now profile the DNA methylome at the genome scale with single-nucleotide resolutio”
DNA Methylation and Its Basic Function (2013, background): “Evidence suggests that DNA methylation of the gene body is associated with a higher level of gene expression in dividing cells (Hellman and Chess, 2007; Ball et al, 2009; Aran et al, 2011).”
Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters (2010, background): “They are (1) promoter islands (if an island ends after 1,000 bp upstream of a RefGene transcription start site, and starts before 300 bp downstream of a RefGene transcription start site); (2) intragenic islands (if an island starts after 300 bp downstream of a RefGene transcription start site and en”
High-resolution genome-wide DNA methylation maps of mouse primary female dermal fibroblasts and keratinocytes (2014, positive): “The hypermethylated regions at the edges of CGIs towards the gene body [18,22] potentially represent methylated exons that are associated with increased gene expression [15,18,23,24].”
Dynamic DNA methylation across diverse human cell lines and tissues (2013, methodology): “To further investigate non-CpG cytosine methylation in the brain, we per- formed RRBS on brain samples from 24 additional individuals.”
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles (2012, methodology): “There are multiple techniques that leverage high-throughput bisulfite sequencing such as: reduced representation bisulfite sequencing (RRBS)[10] and its variants [11], wholegenome shotgun bisulfite sequencing (BS-seq) [12], methylC-Seq [13], and target capture bisulfite sequencing [14].”
Epigenetic memory in induced pluripotent stem cells (2010, background): “While promoter methylation is repressive, gene body methylation is seen in active genes 37 .”
An Integrated Encyclopedia of DNA Elements in the Human Genome (2012, background): “Similarly, DNA methylation shows marked distinctions between segments, recapitulating the known biology of predominantly unmethylated active promoters (TSS states) followed by methylated gene bodies 42 (T state, Figure 5D).”