Pathogenesis and pathophysiology of pneumococcal meningitis.

By U. Koedel, W. Scheld, H. Pfister. Lancet. Infectious Diseases (Print), 2002

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Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses (2009, background): “pneumoniae is diverse, with invasive pneumococcal diseases such as pneumonia, sepsis, and meningitis representing a significant burden of disease in both developing and developed countries (192).”
Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain (2013, background): “In summary multiple chemokines have been reported to be upregulated in pneumococcal meningitis that primarily have a role in attracting leukocytes to the CSF, though the roles of many chemokines in the pathogenesis of the disease have not yet been investigated [86].”