Optogenetic interrogation of neural circuits: technology for probing mammalian brain

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Molecular and cellular approaches for diversifying and extending optogenetics. (2010, background): “In addition to these circuit element targeting considerations, the light intensity and wavelength, promoter choice, virus titer, virus tropism, time of opsin expression, target cell biophysics, and local patterns of endogenous activity and modulation will all affect optogenetic inhibition efficacy a”
Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations (2013, background): “For instance, one common strategy to express a tool in a particular cell type and brain region is to use local injections of Cre-dependent viruses into genetically engineered mice that express Cre recombinase in a specific cell type (Zhang et al., 2010).”