Measuring phase-amplitude coupling between neuronal oscillations of different frequencies.

By A. Tort, Adriano B. L. Tort, Robert W. Komorowski, Howard Eichenbaum, Nancy J. Kopell. Journal of Neurophysiology, 2010

1,326 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/6735ff5ee86c8c818cdb7708f05fde1f29d224d9

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Mechanisms of Gamma Oscillations (2012, background): “…underlie CFPA coupling in most situations, but convincing demonstration of clear phase-phase coupling is hampered by the lack of adequate methods to quantify cross-frequency interactions and reliably track the true phase of nonharmonic oscillators (Tort et al. 2010, Belluscio et al. 2012).”
Complex oscillatory waves emerging from cortical organoids model early human brain network development (2019, methodology): “Modulation Index was computed as the Kullback-Leibler divergence between the sum-normalized distribution of gamma power across phase bins and a uniform distribution (Tort et al., 2010).”
Electroencephalogram signatures of loss and recovery of consciousness from propofol (2013, neutral): “To investigate further the structure in the prominent low-frequency and alpha oscillations observed during unconsciousness, we analyzed phase– amplitude modulation between the rhythms (35).”
Untangling cross-frequency coupling in neuroscience (2014, neutral): “This is all that is needed to give rise to phase– amplitude CFC, as measured for example by the modulation index [26].”
The Theta-Gamma Neural Code (2013, neutral): “Theta-Gamma Coupling—Several signal processing tools have been developed to quantify theta-gamma coupling (more generally termed cross-frequency coupling) (Canolty et al., 2006; Cohen, 2008; Kramer et al., 2008; Onslow et al., 2011; Penny et al., 2008; Tort et al., 2010; Young and Eggermont, 2009).”
Speech Rhythms and Multiplexed Oscillatory Sensory Coding in the Human Brain (2013, methodology): “This map corresponds to Figure 4A but is computed using a different method for quantifying cross-frequency coupling [76].”
Theta power reduction and theta–gamma coupling desynchronization are associated with working memory interference and anxiety symptoms in panic disorder: a retrospective study (2024, unknown): “The MI was calculated using the following formula: MI = log(N) ˗ H(P) / log(N), where N, log(N), and H(P) represent the number of phase bins, entropy of uniform distribution, and entropy of P, respectively [65, 66].”
The Functional Interactions between Cortical Regions through Theta-Gamma Coupling during Resting-State and a Visual Working Memory Task (2022, methodology): “The KL distance formula resembles the definition of the entropy of P, H(P) defined by [89]:”
Targeting neural oscillations with transcranial alternating current stimulation (2021, background): “Then, this hybrid signal is averaged over time and the magnitude of the resulting vector is the PAC strength, referred to as mean vector length (Cohen, 2014; Tort, 2010; Canolty, 2006).”
Non-Target Suppression Supports the Formation of Representational Prioritization Under High Working Memory Load (2025, unknown): “The modulation index (MI) was calculated to assess the degree of PAC [40]; a higher MI indicates stronger coupling between the two frequency bands.”
Mechanisms and Controversies of tACS (Transcranial Alternating Current Stimulation) (2024, background): “Another cross-frequency mechanism, more extensively observed in cognitive neuroscience, is phase-amplitude coupling (PAC) (Jensen & Colgin, 2007; Tort et al., 2010).”