Mechanisms of ischemic brain damage.
By K. Doyle, Roger Simon, Mary P. Stenzel-Poore. Neuropharmacology, 2008
962 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Neurology
View Paper: https://www.semanticscholar.org/paper/6693a94c82d8b560e56303326c2ce86da60b17cb
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In Cellular and Molecular Neuroscience
In Neurology
Citations in the corpus
- Mitochondria, oxidative metabolism and cell death in stroke. (2010, positive): “Early studies demonstrated that pharmacological blockade of ionotropic glutamate receptors markedly reduced ischemic damage [2,15,20].”
- Plasticity during stroke recovery: from synapse to behaviour (2009, background): “Here, we concentrate on the events that are associated with recovery from stroke damage and not the initial mechanisms of ion imbalance or cell death that are reviewed elsewher”
- Stroke in the 21st Century: A Snapshot of the Burden, Epidemiology, and Quality of Life (2018, background): “A vicious cycle (ischaemic cascade) ensues due to accumulation of sodium, calcium, and water in the injured brain cells, which lead to release of excitatory neurotransmitters causing further cell injury [56, 57].”
- Mitochondrial dysfunction and oxidative stress in metabolic disorders - A Step towards mitochondria based therapeutic strategies (2016, result): “In focal ischemia, the damaging action of oxidative stress in necrosis and apoptosis has been explained in previous studies [160,161].”
- Glutamate Receptor Ion Channels: Structure, Regulation, and Function (2010, background): “Stroke and TBI trigger a number of potentially neurotoxic cascades in addition to NMDA receptor-mediated toxicity (Lo et al., 2003, 2005; Rogalewski et al., 2006; Doyle et al., 2008; Green, 2008).”
- Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy (2017, background): “Brain injury from ischemia can occur from excitotoxicity, acidosis, ionic imbalance and depolarization, oxidative stress, nitrative stress, inflammation, and apoptosis (38).”
- Potential therapeutic uses of BDNF in neurological and psychiatric disorders (2011, background): “Stroke is the most common disorder of the nervous system and is the third leading cause of deaths in the United State”