Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

By Jing He, Louis M. Tsai, Y. A. Leong, Xin Hu, Cindy S. Ma, N. Chevalier, Xiaolin Sun, K. Vandenberg, S. Rockman, Yan Ding and 17 more. Immunity, 2013

616 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/379ebc7fd6a30e017372d76cde6972043425dcea

How researchers see this paper

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In Immunology

1. Shane Crotty
2. Carola G. Vinuesa
3. Di Yu
4. Michael Thomas Wong
5. Evan W. Newell

Citations in the corpus

• Mapping the Diversity of Follicular Helper T Cells in Human Blood and Tonsils Using High-Dimensional Mass Cytometry Analysis. (2015, background): “Future studies should also address the functional relevance of the numerous subtypes of TFH cells, as well as determine their association with clinical parameters such as age or response to vaccination similar to previous studies (Bentebibel et al., 2013; He et al., 2013; Locci et al., 2013).”
• Follicular Helper T Cells. (2016, background): “Upon antigen reexposure, these circulating pre-Tfh cells rapidly differentiate into GC Tfh cells and support antibody responses (60).”
• T follicular helper cell biology: A decade of discovery and diseases (2019, background): “Activated cTfh cells are most likely derived from GC-Tfh cells (Heit et al., 2017; Locci et al., 2013) or fTfh cells (He et al., 2013; Tsai and Yu, 2014).”