The interplay between cell signalling and the mevalonate pathway in cancer
By P. Mullen, Rosemary Yu, Joseph Longo, M. C. Archer, Linda Z. Penn. Nature Reviews. Cancer, 2016
618 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/65a01965944a00a1e0d855fd62a0df823b265f21
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In Cancer Research
In Molecular Biology
Citations in the corpus
- Ferroptosis: mechanisms and links with diseases (2021, background): “IPP is catalyzed into CoQ10 through various enzymatic steps,(137) including two major intermediates, farnesyl diphosphate (FPP) and geranylgeranyldiphosphate (GGPP).(138)”
- Mutant p53 as a guardian of the cancer cell (2018, neutral): “The MVP produces sterols and isoprenoids required for synthesis of membranes and lipid rafts, signal transduction and protein prenylation [41].”