Gibberellin-induced DELLA recognition by the gibberellin receptor GID1

By K. Murase, Y. Hirano, Tai-ping Sun, T. Hakoshima. Nature, 2008

701 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Regulation of flowering time: all roads lead to Rome (2011, background): “It was shown recently that the GA-bound form of GID1 induced a conformational change upon binding to the N-terminal region of DELLA proteins [139].”
d14, a strigolactone-insensitive mutant of rice, shows an accelerated outgrowth of tillers. (2009, background): “…revealed that, instead of acting as a nucleophile that attacks a carbonyl carbon to initiate hydrolysis, the conserved serine residue in the catalytic triad of GID1 is responsible for forming a hydrogen bond with the carboxyl group of gibberellins (Murase et al. 2008, Shimada et al. 2008).”
Molecular Basis of the Core Regulatory Network in ABA Responses: Sensing, Signaling and Transport (2010, background): “Gibberellin-bound GID1 induces a coil-to-helix conformational transition in its DELLA binding partner, which stimulates the recognition of DELLA by the ubiquitin ligase E3 complex ( Murase et al. 2008 ).”