Liver fibrosis and repair: immune regulation of wound healing in a solid organ

By A. Pellicoro, P. Ramachandran, J. Iredale, J. Fallowfield. Nature reviews. Immunology, 2014

1,269 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/6373d8450b0438c938081a3fb9d799a305b0e913

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Citations in the corpus

Senescence and aging: Causes, consequences, and therapeutic avenues (2018, background): “Cirrhosis is the pathological outcome from liver fibrosis and nonalcoholic fatty liver disease, which in turn is a result of hepatic steatosis, the abnormal accumulation of lipids in hepatocytes (Pellicoro et al., 2014; Hardy et al., 2016).”
Pattern recognition receptors in health and diseases (2021, background): “The inflammatory phase of the wound healing cascade is the decisive stage of wound development, and studies have found that certain members of innate immunity play an important role in the pathogenesis of chronic wound healing abnormalities.(428,429) The signaling pathway of intracellular TLRs is sh”
Hepatic fibrosis: Concept to treatment. (2015, background): “Moreover, under the assumption 5 vol. 62 j S15–S24 S17 A B T cell Cholangiocytes Myofibroblast Macrophage Hepatic stellate cell CCL2, IL-1β, IL-6 ROS, NO PDGF-BB, ET-1, IL-1, IL-6, TNFα IL-17, IL-22, IFNγ IFNγ, TNFα, IL-4, IL-5, IL-13 IL-1β, TNFα, NO IL17 , T GF β1 TG Fβ 1, IL -6 , I FN γ PDGF-BB, E”
Ultrasound Elastography: Review of Techniques and Clinical Applications (2017, background): “The multiple causes of CLD (including hepatitis viral disease, nonalcoholic fatty liver disease, alcoholic liver disease and autoimmune liver disease) follow a common pathway towards liver fibrosis and finally cirrhosis, increasing the risk for the development of portal hypertension (PH), hepatic in”
Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues. (2019, background): “CLD (Pellicoro et al., 2014), with IL-13 being the most relevant mediator at least in experimental model of liver fibrosis (Chiaramonte et al.”
Hepatic stellate cells as key target in liver fibrosis (2017, background): “nucleotides can contribute to initiation of HSC activation [8,41,42].”
Hepatic Inflammation and Fibrosis: Functional Links and Key Pathways (2015, background): “Accordingly, hepatic macrophages are often found in close proximity to fibrotic scars.(21) Of note, macrophages have divergent functions in fibrogenesis and specific populations also promote fibrosis resolution through enhanced ECM degradation by increased matrix metalloproteinase (MMP)212 and MMP-1”