Preconditioning the myocardium: from cellular physiology to clinical cardiology.

By D. Yellon, J. Downey. Physiological Reviews, 2003

1,145 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/633d338a0ed3ab695fa4facacbb7692071346654

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. G. Heusch
2. M. A. Talukder
3. Jay L. Zweier

In Developmental Neuroscience

1. G. Heusch
2. M. A. Talukder
3. Jay L. Zweier
4. B. J. Gersh
5. D. Hausenloy
6. D. Yellon

In Pathology and Forensic Medicine

1. G. Heusch
2. E. Murphy
3. C. Steenbergen
4. D. Yellon
5. D. Hausenloy
6. B. J. Gersh
7. M. A. Talukder
8. Jay L. Zweier

Citations in the corpus

• The role of oxidants and free radicals in reperfusion injury. (2006, positive): “There is evidence that ischemic preconditioning (IPC) may be induced by low level oxidant formation during the brief periods of preconditioning ischemia and reflow [102].”
• Calcium, ATP, and ROS: a mitochondrial love-hate triangle. (2004, background): “protect against injury from a large ischemic event (215, 223).”
• Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. (2008, background): “…preconditioning, which are primarily mediated by gene induction and protein synthesis; the reader is referred to other excellent reviews on this topic (237, 282) Section V will summarize how the acute cardioprotective signaling pathways activated by pre-and postconditioning might reduce cell death.”
• Inwardly rectifying potassium channels: their structure, function, and physiological roles. (2010, background): “This phenomenon is called ischemic preconditioning (547, 871).”
• Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning. (2015, methodology): “for IPC, which uses a logical/causal sequence of events which coincides with the temporal sequence of protocol steps.(41,42) A”
• The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge. (2016, background): “Experimental studies over the last three decades have identified complex signal transduction processes underlying the cardioprotection by ischaemic preconditioning, ischaemic postconditioning, and remote ischaemic conditioning.(97) – 99 The local ischaemic pre- and postconditioning phenomena are ini”
• New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway. (2004, background): “Given the mounting evidence supporting the role of pro-survival kinases inducing protection at reperfusion , we recently postulated that IPC may also mediate cardio-protection by up-regulating the pro-survival PI3K – Akt and Erk 1/2 kinase signalling cascades, at the time of reperfusion, following t”