Shared Pathways of IκB Kinase-Induced SCFβTrCP-Mediated Ubiquitination and Degradation for the NF-κB Precursor p105 and IκBα

By V. Heissmeyer, D. Krappmann, E. Hatada, C. Scheidereit. Molecular and Cellular Biology, 2001

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Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation (2003, methodology): “M -mercaptoethanol. Stable 1.3E2 IKK clones were generated as described previously ( 12 ), and cells were maintained with 1 g of G418 per ml of medium.”
NF-κB, the first quarter-century: remarkable progress and outstanding questions. (2012, background): “2004), and p105 (Orian et al. 2000; Heissmeyer et al. 2001) also possess similarly defined degrons.”