Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin.
By J. Varani, R. Warner, M. Gharaee‐Kermani, S. Phan, Sewon Kang, J. Chung, Zengquan Wang, Subhash C. Datta, G. Fisher, J. Voorhees. Journal of Investigative Dermatology, 2000
611 citations recorded by the source corpus.
Subfields: Dermatology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/62d3a2963eae85fba3406d7aa659d6c0acd481a4
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In Dermatology
Citations in the corpus
- Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. (2006, methodology): “The enzymes responsible for collagen degradation increase gradually over time in the skin.(15) Collagen synthesis may also decline gradually, but the fall-off in new collagen production is most evident when skin damage is clinically evident.”
- Applications for Marine Resources in Cosmetics (2017, background): “Inhibitors of matrix metalloproteinase (MMPs) may have potential utility as an anti-wrinkle cosmetic product [47].”
- Skin ageing and its treatment (2007, background): “For example, collagen production has been shown to be stimulated by the use of retinoids [84], vitamin C [85] and copper peptide.”
- Skin anti-aging strategies (2012, background): “Although the technology required to suitably deliver these compounds into the skin has not yet been developed, some products do promote the natural synthesis of these substances except elastin enhancing.(42-45) Another integral approach preventing wrinkle formation is the reduction of inflammation b”