Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies.

By J. Belle, Martin Heisenberg. 1994

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Citations in the corpus

Re-evaluating circuit mechanisms underlying pattern separation (2019, positive): “Early lesion and ablation experiments identified the mushroom body as a centre for olfactory memory and associative learning in insects (de Belle and Heisenberg, 1994; Connolly et al., 5 1996).”
Dopaminergic neurons write and update memories with cell-type-specific rules (2016, background): “DOI: 10.7554/eLife.16135.001”
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, positive): “DOI: 10.7554/eLife.04580 2 of 42 Research article The mushroom body (MB) is the main center of associative memory in insect brains (de Belle and Heisenberg, 1994, Heisenberg et al., 1985; Dubnau et al., 2001; McGuire et al., 2001).”
Recognition (2003, neutral): “…body (MB)/Kenyon cells (KCs) in insects—where sparse combinatorial codes are translated into associative memories, patterns, and behavioral decisions (de Belle & Heisenberg, 1994; Dubnau et al., 2001; Heisenberg et al., 1985; McGuire et al., 2001; Davison & Ehlers, 2011; Miyamichi et al., 2011).”
The neuronal architecture of the mushroom body provides a logic for associative learning (2014, background): “Olfactory memory formation and retrieval in insects require the mushroom body (MB) (Heisenberg et al., 1985; de Belle and Heisenberg, 1994, *For correspondence: asoy@ janelia.hhmi.org (YA); rubing@ janelia.hhmi.org (GMR) Competing interests: The authors declare that no competing interests exist.”
Drosophila α/β Mushroom Body Neurons Form a Branch-Specific, Long-Term Cellular Memory Trace after Spaced Olfactory Conditioning (2006, unknown): “Why is it that a memory trace representing early memories was not discovered during these studies, given that the MBs have been widely implicated in all temporal phases of memory? For instance, ablation of the MBs during development by hydroxyurea poisoning impairs the memory of adult flies immediat”
The organization of extrinsic neurons and their implications in the functional roles of the mushroom bodies in Drosophila melanogaster Meigen. (1998, background): “The Drosophila mushroom bodies appear to play a role only in olfactory learning, because mushroom body ablation does not affect visual learning (deBelle and Heisenberg 1994).”
Functional analysis of a higher olfactory center, the lateral horn (2012, background): “Abolishing the MB in Drosophila was linked to deficits in olfactory learning but had little effect on innate olfactory behaviors (de Belle and Heisenberg, 1994; Kido and Ito, 2002).”
Generating sparse and selective third-order responses in the olfactory system of the fly (2010, background): “The mushroom body is implicated in decision making (11) and in the formation of associative memories (12, 13).”
Functional dissection of the Drosophila mushroom bodies by selective feminization of genetically defined subcompartments. (1995, background): “These have been invoked as centers for courtship behavior in other insects (Huber, 1960; Wahdepuhl, 1983)and have also been implicated in olfactory processing and learning (Heisenberg; 1989; Davis, 1993; de Belle and Heisenberg, 1994).”