Inflammaging: a new immune–metabolic viewpoint for age-related diseases

By Claudio Franceschi, Paolo Garagnani, P. Parini, C. Giuliani, A. Santoro. Nature Reviews Endocrinology, 2018

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Aging and aging-related diseases: from molecular mechanisms to interventions and treatments (2022, background): “immunity and metabolism due to its close association with other organs and tissues in the body.(194) Aging-related alterations in the gut microbiota promote the development of systemic inflammation, which can have profound effects on disease, either directly or indirectly.”