Computational design of a symmetric homodimer using β-strand assembly

By P. Benjamin Stranges, M. Machius, M. Miley, A. Tripathy, Brian Kuhlman. 2011

74 citations recorded by the source corpus.

Subfields: Materials Chemistry, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Materials Chemistry

1. I. Samish
2. Sagar D. Khare
3. Sarel Jacob Fleishman

In Molecular Biology

1. I. Samish
2. Sagar D. Khare
3. Sarel Jacob Fleishman
4. David Baker

Citations in the corpus

• Achievements and Challenges in Computational Protein Design. (2017, background): “In 2011 the Kuhlman lab designed a symmetric homodimer using β-strand assembly in which two solvent-exposed strands were designed to form an antiparallel β-strand pairing [88].”
• Emerging themes in the computational design of novel enzymes and protein–protein interfaces (2013, background): “This inference led to the design of a symmetric homodimer mediated by a cross-interface b sheet [48].”
• Protein Engineering by Combined Computational and In Vitro Evolution Approaches. (2016, unknown): “More recently, it has also been used to create novel binding interactions [21–23].”