Combining radiotherapy and cancer immunotherapy: a paradigm shift.

By S. Formenti, S. Demaria. Journal of the National Cancer Institute, 2013

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Immune Checkpoint Blockade in Cancer Therapy. (2015, background): “Targeted therapy directed at oncogenic signaling pathways, such as the BRAF mutation in melanoma, is also an attractive partner to combine with immune checkpoint blockade based on preclinical data, as reviewed by Hu-Lieskovan et al.93 The combination of ipilimumab and vemurafenib resulted in frequen”
Radiomics: the bridge between medical imaging and personalized medicine (2017, positive): “The stimulation of an antitumour immune response in response to radiotherapy has been well documented 92 .”
Designer vaccine nanodiscs for personalized cancer immunotherapy (2016, positive): “These issues may be tackled in the future by multi-thronged strategies that exploit combined immunotherapy targeted to humoral and innate arms of immunity 36 or radiation therapy 37 and select chemotherapeutics 38 known to delay tumor growth and synergize with T-cell vaccines.”
An Abscopal Response to Radiation and Ipilimumab in a Patient with Metastatic Non-Small Cell Lung Cancer (2013, background): “with metastatic disease that are historically known to have dismal prognoses (3).”