Physical Mechanisms of Inactivation of Bacillus subtilis Spores Using Cold Atmospheric Plasmas

By Jianjun Shi, Michael G. Kong. IEEE Transactions on Plasma Science, 2006

311 citations recorded by the source corpus.

This paper presents a detailed study of the potential physical mechanisms of the microbial inactivation by cold atmospheric plasmas. With the Bacillus subtilis spores as a model microorganism and an atmospheric-plasma plume in helium flow, optical emission spectroscopy and inactivation kinetics are used to demonstrate the dominating role played by the reactive oxygen species (e.g., atomic oxygen and OH) as well as the minor contributions of the UV photons, heat, charged particles, and electric fields. To differentiate the concentrations of the reactive oxygen species, an atmospheric helium-oxygen plasma is also used for the spore inactivation. Results with the helium and the helium-oxygen plasmas are contrasted to highlight how the production of the spore-killing oxygen species may be enhanced

Subfields: Electrical and Electronic Engineering, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/60dea885144dbcd94af60f5e305416935ff6fbb2

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Citations in the corpus

Plasma medicine: an introductory review (2009, unknown): “…effective against gram-negative than gram-positive bacteria and they can cause severe damages to membranes of microorganizms as shown in ﬁgure 7, where the Bac Light method is used to identify intact and bleached membranes of B. subtilis spores with green and red ﬂorescence, respectively [130].”
Applied Plasma Medicine (2008, background): “atomic oxygen and OH) with minor aid from UV photons, charged particles, heat, and electric fields [68, 71, 73, 74, 76, 77].”