APOBEC3B is an enzymatic source of mutation in breast cancer

By Michael B. Burns, Lela Lackey, M. Carpenter, Anurag Rathore, Allison M. Land, B. Leonard, Eric W. Refsland, Delshanee Kotandeniya, N. Tretyakova, Jason B. Nikas and 7 more. Nature, 2013

841 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Virology

View Paper: https://www.semanticscholar.org/paper/299c423b08b4cbba86b6026777dfb5bf128ba146

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In Molecular Biology

1. S. Tsai
2. Deepak Reyon
3. Martin J. Aryee
4. Jennifer A. Foden
5. Cyd Khayter
6. J. Keith Joung
7. Jeffry D. Sander
8. Feng Zhang

Citations in the corpus

• Signatures of mutational processes in human cancer (2013, neutral): “Collectively, these studies will advance our understanding of cancer aetiology with potential implications for prevention and treatment.”
• Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing (2014, background): “…within the binding site is a cytosine preceded by a thymine on the non-complementary strand, perhaps suggesting the involvement of APOBEC proteins that preferentially recognize and deaminate cytosines at TC sequences and that can be overexpressed in transformed cancer cell lines 24, 25 .”