The gene encoding the splicing factor SF2/ASF is a proto-oncogene

By R. Karni, E. Stanchina, Scott W. Lowe, Rahul Sinha, D. Mu, Adrian R. Krainer. Nature Structural &Molecular Biology, 2007

937 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5f85c528919be955f619a572fdfd008429c8a8ce

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In Molecular Biology

1. J. Manley
2. Qun Pan
3. Benjamin J. Blencowe
4. Charles J. David
5. C. F. Bennett
6. Susan M. Freier
7. Asfar S. Azmi
8. S. Prasanth

Citations in the corpus

• Broad targeting of resistance to apoptosis in cancer (2015, background): “Factors such as SF2/ASF and SC35 are associated with transformation may be upregulated in some tumors [123].”
• The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation (2010, background): “These AS events were previously reported to be sensitive to cellular levels of SRSF1 (Karni et al., 2007).”
• Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. (2010, background): “Consistent with this, Krainer and colleagues (Karni et al. 2007) demonstrated that the gene encoding SRSF1 can function as a proto-oncogene.”