An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles

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Treating metastatic cancer with nanotechnology (2011, background): “Computed tomography contrast agents often involve small molecules with short half-lives in the bod”
Computationally Guided Photothermal Tumor Therapy Using Long-Circulating Gold Nanorod Antennas (2009, background): “Previously, polymer-stabilized inorganic nanomaterials have been described with circulation half-lives of a few hours in vivo (29, 30), including a variety of other gold nanoparticle preparations (22, 31–33), and on occasion with circulation times of f10 to 15 hours in mice (21, 28, 34).”
A review of imaging techniques for systems biology (2008, methodology): “In the future, nanoshells may provide excellent contrast for other imaging modalities such as CT [ 96 ].”
Nanomedicine for drug delivery and imaging: A promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles (2007, background): “Most recently, this group also developed another new X-ray-computed tomography imaging agent based on bismuth sulfide nanoparticles.(88) This polymer-coated Bi2S3 nanoparticles have a long circulation time and a high X-ray absorption, and can enhance imaging of vasculature.”