Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy.

By Alexandru Almasan, A. Ashkenazi. Cytokine & growth factor reviews, 2003

595 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5eb33fce4897807bcd272562c2b600aa125ea845

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Citations in the corpus

• A cytokine-mediated link between innate immunity, inflammation, and cancer. (2007, unknown): “TRAIL is a potent inducer of tumor cell death (40), but in this mouse model of transplanted metastatic cancer, its tumoricidal activity was evident only upon inhibition of NF-k B activity in the tumor cells (39).”
• Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies (2016, background): “An example of such therapeutic strategy is represented by the ligand TRAIL known to induce apoptosis in different tumor cell lines [77].”