NADPH Oxidases: Functions and Pathologies in the Vasculature

By B. Lassègue, K. Griendling. Arteriosclerosis, Thrombosis and Vascular Biology, 2010

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How researchers see this paper

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Crosstalk between mitochondria and NADPH oxidases (2011, background): “Over the past several years, it has become clear that reactive oxygen species (ROS) play an important role in both physiological and pathological processes [1,2].”
The Role of Oxidative Stress in Neurodegenerative Diseases (2015, background): “It also modulates various cellular activities including gene expression, mitosis, proliferation, migration, cell survival, and apoptosis [5, 58, 60].”
Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases (2011, positive): “Low levels of either intracellular or extracellular ROS ( e.g. , superoxide and H 2 O 2 ) are indispensable in many biochemical processes, including intracellular signaling, defense against microorganisms, and cell function (74, 125, 223).”
Endothelial dysfunction - a major mediator of diabetic vascular disease. (2013, background): “with different cell-specific expression, mode of activation and function (for a review see [111, 113]).”