Nonalcoholic fatty liver disease.

By P. Angulo. Revista de Gastroenterología de México, 2002

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Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases (2017, background): “6 – 8 Highlighting the intimacy of these associations is the observation that the increases in hepatic lipid accumulation are directly proportional to the severity of each component of the metabolic syndrome.”
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD). (2016, background): “[1] Angulo P.”
Role of Oxidative Stress in Pathophysiology of Nonalcoholic Fatty Liver Disease (2018, background): “The presence of a significant (>5% of hepatocytes) fat accumulation in the liver, in the absence of an “unsafe” quantity of alcohol consumption and any other cause of liver diseases, is a potentially pathological condition that is defined as nonalcoholic fatty liver disease (NAFLD) [1].”
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease. (2019, background): “DISCUSSION Steatosis is the hallmark feature of NAFLD and precedes the progression to steatohepatitis and fibrosis (36).”