Regular Physical Activity Improves Endothelial Function in Patients With Coronary Artery Disease by Increasing Phosphorylation of Endothelial Nitric Oxide Synthase
By R. Hambrecht, V. Adams, S. Erbs, A. Linke, N. Kränkel, Y. Shu, Y. Baither, S. Gielen, H. Thiele, J. Gummert and 2 more. Circulation, 2003
961 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/5deb53d72ea3c168b221848009b945fd844c2459
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In Cardiology and Cardiovascular Medicine
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Citations in the corpus
- Effects of exercise and diet on chronic disease. (2005, background): “In a series of studies, Hambrecht and colleagues (128, 130) established that exercise training improves endothelium-dependent vasodilation in patients with CAD and chronic heart failure and provided evidence that improvement of endothelial function is associated with increased endothelial NO synthas”
- Updating the evidence that physical activity is good for health: an epidemiological review 2000-2003. (2004, background): “Biological mechanisms are being explored, with effects of exercise apparent on cardiac endothelial function(30, 31 ).”
- Cardiovascular Effects and Benefits of Exercise (2018, background): “In patients with stable CAD, 4 weeks of rowing or cycling led to enhanced vasodilatory responses to acetylcholine, which was associated with increased total endothelial nitric oxide synthase (eNOS) expression and eNOS, and protein kinase B (Akt) phosphorylation (27).”
- Cardiovascular actions of insulin. (2007, background): “dase and angiotensin-II type 1 receptor AT1-R expression in tissue specimens of the left internal mammary artery harvested during coronary bypass surgery (410, 411).”
- Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. (2005, background): “However, in trials of patients with hypertension, hypercholesterolemia, diabetes, coronary artery disease, or heart failure, aerobic exercise has been shown to increase nitrous oxide and prostacyclin availability and to improve endothelial-dependent vasodilatation (29, 30, 71, 82, 103).”
- The role of shear stress in the pathogenesis of atherosclerosis (2005, background): “118 Related studies have also shown that shear stress induced by exercise induces enhanced S1179 phosphorylatio”
- Effect of exercise training on endothelium‐derived nitric oxide function in humans (2004, background): “In the most recent of their impressive series of studies on exercise training on vascular function, Hambrecht et al. (2003) examined the effects of 4 weeks of cycle ergometer exercise on ACh responses in the left internal mammary artery of patients with stable CAD and in matched controls.”
- Endothelial dysfunction and vascular disease – a 30th anniversary update (2017, background): “…explaining the beneficial effects of regular exercise on endothelial function (Miller & Vanhoutte 1988, Mombouli et al. 1996, Davis et al. 2001, Hambrecht et al. 2003, Suvorava et al. 2004, Watts et al. 2004, Lauer et al. 2005, Gertz et al. 2006, Rakobowchuk et al. 2008, Tarhouni et al. 2013,…”
- Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli. (2017, background): “Data from the harvested arteries indicated a 2-fold increase in endothelial nitric oxide synthase (eNOS) expression and 4-fold higher eNOS Ser 1177 phosphorylation after 4-weeks training (114).”