Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study.

By Scott L. Rauch, P. Whalen, Lisa M. Shin, S. McInerney, M. L. Macklin, N. Lasko, Scott P. Orr, R. Pitman. Biological Psychiatry, 2000

1,109 citations recorded by the source corpus.

Subfields: Clinical Psychology, Cognitive Neuroscience, Epidemiology

View Paper: https://www.semanticscholar.org/paper/5dd00f4b565490f4b15648455785bbb41ad890a9

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Citations in the corpus

Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. (2004, background): “Likewise, we found correlations between anxiety andamygdala (Rauch et al., 2000; Whalen et al., 1998).”
Fear extinction in rats: implications for human brain imaging and anxiety disorders. (2006, background): “Patients with PTSD exhibit exaggerated amygdala responses when viewing masked-fearful faces (Rauch et al., 2000) and during the processing of auditory stimuli (Semple et al., 2000).”
Depression: perspectives from affective neuroscience. (2002, background): “…has also been recently reported in bipolar depression (Ketter et al. 2001) and anxiety disorders, which often show a high degree of comorbidity with depression (Birbaumer et al. 1998; Liberzon et al. 1999; Rauch et al. 1996, 2000; Schneider et al. 1999; Semple et al. 2000; Shin et al. 1997).”
Trauma modulates amygdala and medial prefrontal responses to consciously attended fear (2006, methodology): “By contrast, medial prefrontal activity was absent in both traumatized and nontraumatized subjects in a previous study of masked fearful faces (Rauch et al., 2000), feasibly reflecting different task demands.”
Dissociation Following Traumatic Stress Etiology and Treatment (2010, result): “This finding is consistent with the observation that PTSD patients react to threatening cues and trauma reminders with a hypersensitive alarm system (Rauch et al., 2000).”
Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future. (2006, methodology): “Using a functional agnetic resonance imaging (fMRI) probe of amygdala response Whalen et al 1998b), Rauch et al (2000) found that in comparson with trauma-exposed subjects without PTSD, subjects with TSD exhibited exaggerated amygdala responses to passively iewed masked fearful versus masked happy…”
Source monitoring 15 years later: What have we learned from fMRI about the neural mechanisms of source memory? (2009, background): “Although the picture regarding neural mechanisms associated with this attentional bias is not entirely clear, differences in several brain areas have been implicated, including medial prefrontal cortex, orbitofrontal cortex, parietal regions, anterior cingulate cortex, and amygdala (Liberzon et al.,”
Recognizing emotion from facial expressions: psychological and neurological mechanisms. (2002, background): “…faces of fear Vuilleumier, Armony, Driver, & Dolan (2001) Fear faces Attentional modulation to fear faces in fusiform gyrus but not in left amygdala Rauch et al. (2000) Masked fearful and happy faces Exaggerated amygdala response in patients with post-traumatic stress disorder Baird et al. (1999)…”
The Role of Sleep in Emotional Brain Function (2014, background): “…reported in several affective psychopathologies, including major depression, bipolar disorder, generalized anxiety disorder and PTSD (Davidson 2002, Drevets et al 2008, Etkin 2010, Etkin & Wager 2007, Nitschke et al 2009, Paulus & Stein 2006, Rauch et al 2000, Shin et al 2006, Siegle et al 2007).”