Glycosaminoglycans and their proteoglycans: host‐associated molecular patterns for initiation and modulation of inflammation

By K. Taylor, R. Gallo. The FASEB Journal, 2006

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Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions (2013, background): “Fibroblasts recruited to the wound bed produce proinflammatory cytokines that, in turn, stimulate endothelial cells to produce HA, further promoting the adhesion of cytokine-activated lymphocytes through the HA-binding variant of CD44 [116].”
Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain (2009, background): “Although generally not considered as a major factor in the innate immune response, ECM-based ligands in all tissues can both upregulate and downregulate immune signaling (Morwood and Nicholson 2006; Taylor and Gallo 2006).”
The magic glue hyaluronan and its eraser hyaluronidase: a biological overview. (2007, background): “These interactions mediate three important physiological processes: signal transduction, the formation of pericellular coats and receptor-mediated internalization (Laurent et al., 1996; Vercruysse et al., 1999; Toole et al., 2002; Turley et al., 2002; Toole, 2004; Spicer and Tien, 2004; Adamia et al”