The therapeutic potential of neural stem cells

By G. Martino, S. Pluchino. 2006

763 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Genetics

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. A. Kriegstein
2. Arturo Alvarez-Buylla
3. M. Schwartz
4. M. Elnaggar
5. G. Martino
6. Richard J. Gilbertson
7. Giorgia Quadrato
8. S. Pluchino

In Developmental Neuroscience

1. A. Kriegstein
2. Arturo Alvarez-Buylla
3. S. Pluchino
4. G. Martino
5. L. Bonfanti
6. M. Schwartz
7. M. Elnaggar
8. Richard J. Gilbertson

In Genetics

1. Arturo Alvarez-Buylla
2. Richard J. Gilbertson
3. A. Kriegstein

Citations in the corpus

• Adult neurogenesis in brain repair: cellular plasticity vs. cellular replacement (2014, background): “Indeed there is general agreement that transplanted stem cells play various other roles beside cellular replacement in the diseased/damaged brain including neuroprotection and reduction of the inflammatory response via a bystander effect (Martino and Pluchino, 2006; Martino et al., 2011).”
• Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease (2009, background): “Recent studies, however, demonstrate that stem cell-based approaches can provide beneficial effects via alternative mechanisms, providing what is often referred to as a ‘‘bystander effect’’ (28).”
• The Glial Nature of Embryonic and Adult Neural Stem Cells (2009, background): “Several studies have suggested that the adult SVZ may be an important reservoir of precursor cells for brain repair (Lindvall & Kokaia 2006, Martino & Pluchino 2006).”
• Reactive gliosis and the multicellular response to CNS damage and disease (2014, neutral): “Various cellular regenerative approaches may have potential for CNS repair (Bliss et al., 2007; Martino and Pluchino, 2006; Snyder and Teng, 2012).”
• A perivascular niche for brain tumor stem cells. (2007, background): “Interestingly, atypical ectopic perivascular niches were recently described around perivascular areas of the inflamed CNS (Martino and Pluchino, 2006).”
• BRAIN REGENERATION IN PHYSIOLOGY AND PATHOLOGY: THE IMMUNE SIGNATURE DRIVING THERAPEUTIC PLASTICITY OF NEURAL STEM CELLS (2011, background): “The scarce and inappropriate terminal differentiation, the propensity for maintaining an undifferentiated phenotype within the host tissue, and the colocalization of transplanted NPCs with immune cells within perivascular atypical niches suggested that transplanted NPCs might be therapeutically effi”