A mechanistic overview of translation initiation in eukaryotes
By Colin Echeverría Aitken, J. Lorsch. 2012
436 citations recorded by the source corpus.
Subfields: Literature and Literary Theory
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Citations in the corpus
- Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. (2014, background): “The large (60S) subunit joins at the last step in translation initiation and does not associate with mRNA prior to this time, and so any footprint associated with the 60S subunit derives from a ribosome that has completed initiation and begun translation (Aitken and Lorsch, 2012).”
- The integrated stress response (2016, positive): “It forms a ternary complex with GTP and Met-tRNA i that binds the 40S ribosome subunit, and together with two small initiation factors, eIF1 and eIF1A, it forms the 43S pre-initiation complex (PIC) [89,90].”
- The initiation of mammalian protein synthesis and the mechanism of scanning (2013, methodology): “It is formed by interactions between h18 of the body with h34 and ribosomal protein rpS3(3) of the head, which clamp around the incoming mRNA(29,30).”