Biomaterials & scaffolds for tissue engineering
By F. O'Brien. 2011
2,782 citations recorded by the source corpus.
Every day thousands of surgical procedures are performed to replace or repair tissue that has been damaged through disease or trauma. The developing field of tissue engineering (TE) aims to regenerate damaged tissues by combining cells from the body with highly porous scaffold biomaterials, which act as templates for tissue regeneration, to guide the growth of new tissue. This article describes the functional requirements, and types, of materials used in developing state of the art of scaffolds for tissue engineering applications. Furthermore, it describes the challenges and where future research and direction is required in this rapidly advancing field.
Subfields: Biomaterials, Biomedical Engineering, Surgery
View Paper: https://www.semanticscholar.org/paper/5af5efce93da71ef69a5723aabd3cfaeecec3e1f
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- Chao-lin Tan
- K. Zhou
- Jihang Zou
- Sheng Li
- P. Jamshidi
- Moataz M. Attallah
- Khamis Essa
- A. Abena
Citations in the corpus
- Smart nanoparticles for cancer therapy (2023, background): “36 Polymer micelles can simply physically encapsulate (solubilize) hydrophobic drugs in their hydrophobic core effectively, resulting in the following advantages: (i) elimination of drug side effects; (ii) Increase the water solubility of hydrophobic and insoluble drugs; (iii) Control of drug…”
- Additive manufacturing of bio-inspired multi-scale hierarchically strengthened lattice structures (2021, background): “Scaffold-based bone tissue engineering offers great potential for the treatment of osseous defects [2].”
- Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects (2016, background): “However, all of the previously mentioned biomaterials have some drawbacks: ceramics are too stiff, synthetic polymers—not degradable and natural polymers might possess poor mechanical properties (O’Brien 2011).”