Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells.

By S. Dave, George W. Wright, Bruce K. Tan, A. Rosenwald, R. Gascoyne, W. Chan, R. Fisher, R. Braziel, L. Rimsza, T. Grogan and 30 more. New England Journal of Medicine, 2004

1,431 citations recorded by the source corpus.

Subfields: Neurology, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/5acd46663d72ba12e3df1891120699da4c60b6b8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Oncology

1. Giuseppe Jurman
2. Ralf Küppers
3. U. Kammula
4. D. Calado

In Pathology and Forensic Medicine

1. Ralf Küppers
2. D. Calado

Citations in the corpus

• Mechanisms of B-cell lymphoma pathogenesis (2005, background): “Notably, it was recently shown that the survival of patients with follicular lymphoma is correlated with characteristic features of non-tumour cells in the lymphoma tissu”
• Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes (2012, background): “lung cancer [6–8], lymphomas [9–13], leukemia [14,15], and”
• Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. (2006, background): “Evidence for tumor influence in cancer progression has been shown in recent publications demonstrating the influence of tumor-infiltrating lymphocytes in follicular lymphoma and the role of tumor-educated macrophages in breast carcinoma (Dave et al., 2004; Pollard, 2004).”
• Mass cytometry of follicular lymphoma tumors reveals intrinsic heterogeneity in proteins including HLA-DR and a deficit in non-malignant plasmablast and germinal center B cell populations (2017, background): “FL is named for its follicle-like appearance and is thought to arise from mature germinal center (GC) B cells (2).”
• The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models (2010, background): “Previously, reanalysis of a widely cited single stud”
• Early Relapse of Follicular Lymphoma After Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone Defines Patients at High Risk for Death: An Analysis From the National LymphoCare Study. (2015, background): “In contrast, the immune response 2 signature comprised genes expressed by dendritic cells and macrophages and had worse outcomes.(17) Moreover, other genetic alterations, such as chromosomal gains and losses or rearrangements of P53 or MYC, have been implicated in poor outcomes in FL.”
• Integrative analysis of the cancer transcriptome (2005, methodology): “Putative binding site identification (1) match algorithm (2) rank threshold Differential expression analysis (1) t-test (2) false discovery rate correction”
• Tumor‐associated macrophages (TAM) as major players of the cancer‐related inflammation (2009, neutral): “, CD68) [16, 17].”