Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

By Thomas Graf. 2007

1,838 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/58ba405ae9be9a40bca8ed51a910c3848be59788

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In Molecular Biology

1. S. Yamanaka
2. K. Hochedlinger
3. M. Stadtfeld
4. R. Jaenisch
5. Fred H. Gage
6. Hongjun Song
7. G. Daley
8. Guo-li Ming

Citations in the corpus

• Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer (2013, background): “High oocyte numbers retrieved from an ovarian stimulation cycle are generally associated with poor clinical IVF outcomes (Pellicer et al., 1989; Santos et al., 2010; van der Gaast et al., 2006).”
• Pluripotency: Toward a gold standard for human ES and iPS cells (2009, background): “Using these assays alone may not be JOURNAL OF CELLULAR PHYSIOLOGY sufficient, since studies show that certain cell lines that express appropriate ES markers and pluripotency genes are deficient in functional pluripotency (Lowry et al., 2008; Tateishi et al., 2008).”
• Induced pluripotency: history, mechanisms, and applications. (2010, background): “…animals exhibit subtle to severe phenotypic and gene expression abnormalities, suggesting that SCNT results in faulty epigenetic reprogramming (Wakayama and Yanagimachi 1999; Hochedlinger and Jaenisch 2002b; Humpherys et al. 2002; Ogonuki et al. 2002; Tamashiro et al. 2002; Gurdon et al. 2003).”
• Induced pluripotent stem cells: past, present, and future. (2012, background): “In 2006, we showed that stem cells with properties similar to ESCs could be generated from mouse fibroblasts by simultaneously introducing four genes (Takahashi and Yamanaka, 2006).”
• Brain organoids: advances, applications and challenges (2019, background): “…stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), have emerged as invaluable tools for modeling human disorders, especially those with complex genetic origins that are challenging to model in animals (Takahashi et al., 2007; Takahashi and Yamanaka, 2006; Thomson et al., 1998).”