Chemistry and Biochemistry of Dietary Polyphenols

By R. Tsao. Nutrients, 2010

2,188 citations recorded by the source corpus.

Polyphenols are the biggest group of phytochemicals, and many of them have been found in plant-based foods. Polyphenol-rich diets have been linked to many health benefits. This paper is intended to review the chemistry and biochemistry of polyphenols as related to classification, extraction, separation and analytical methods, their occurrence and biosynthesis in plants, and the biological activities and implications in human health. The discussions are focused on important and most recent advances in the above aspects, and challenges are identified for future research.

Subfields: Biochemistry, Molecular Biology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/58498d40e4d6df76efa642cc94308c819648447b

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Citations in the corpus

Nanoparticles as Novel Elicitors to Improve Bioactive Compounds in Plants (2021, background): “Recently, polyphenols have received the attention of scientists and consumers, due to their potential medicinal properties in the prevention and cure of various degenerative diseases, particularly cancers, cardiovascular diseases and neurodegenerative diseases [81].”
Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action (2022, background): “Phenolics in plant derived foods are basically divided into phenolic acids, flavonoids, and non-flavonoids (Tsao, 2010).”
Polyphenols: Extraction Methods, Antioxidative Action, Bioavailability and Anticarcinogenic Effects (2016, background): “Therefore, free polyphenols along with aglycones, glycosides and oligomers can be readily extracted by solvents such as methanol, ethanol, acetonitrile and acetone, or by their mixtures with water [25].”
A review on health benefits of kombucha nutritional compounds and metabolites (2018, background): “They modulate the activity of a variety of enzymes and cell receptors as a means of defence against oxidative stress caused by reactive oxygen species (Tsao, 2010).”
Honey: Chemical composition, stability and authenticity. (2016, background): “Variations in this structure can be found in methylation and hydroxylation of the aromatic ring (Tsao, 2010).”
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols (2018, background): “They are classified according to their chemical structures into flavonoids such as flavones, flavonols, isoflavones, neoflavonoids, chalcones, anthocyanidins, and proanthocyanidins and nonflavonoids, such as phenolic acids, stilbenoids, and phenolic amides [7].”
Phytochemistry and biological activity of mustard (Brassica juncea): a review (2020, positive): “Compiling data from relevant reports, the nature and chemical structure of 24 reported polyphenol compounds in mustard have been identified (Figure (1)) (Manach et al., 2004; Tsao, 2010).”
Alleviation of salt-induced adverse impact via mycorrhizal fungi in Ephedra aphylla Forssk (2014, methodology): “Phenolic compounds enhance protection against biotic and abiotic stresses by acting as a potential antioxidant particularly to scavenge singlet oxygen (Rice-Evans et al. 1997; Tsao 2010; Pohjala & Tammela 2012).”
Extraction of phenolic compounds: A review (2021, background): “Similarly, they vary in their nature and chemical structure, ranging from simple to highly complex substances with different contents of phenolic acids, anthocyanins, phenylpropanoids, and tannins (Balasundram et al., 2006; Tsao, 2010).”
Immunosenescence and Its Hallmarks: How to Oppose Aging Strategically? A Review of Potential Options for Therapeutic Intervention (2019, background): “They are in fruits, vegetables, grains, and other plant foods, the consumption of which has been linked to reduction in risk of major age-related diseases (141, 142).”