Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion

By Michael Barnett, J. Prineas. Annals of Neurology, 2004

1,246 citations recorded by the source corpus.

Subfields: Neurology, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/57f5a291dbdddd092e45046149404654092e583b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. Hans Lassmann
2. Wolfgang Brück
3. C. Lucchinetti
4. Stephen L. Hauser
5. A. Prat

In Oncology

1. Kate M O'Brien
2. Hans Lassmann
3. Cris S. Constantinescu
4. N. Farooqi
5. B. Gran

In Pathology and Forensic Medicine

1. Hans Lassmann
2. Wolfgang Brück
3. C. Lucchinetti
4. Stephen L. Hauser
5. Jorge R. Oksenberg

Citations in the corpus

• Oxidative damage in multiple sclerosis lesions (2011, background): “This zone is regarded as the initial demyelinating lesion (Marik et al., 2007) or the ‘prephago- cytic’ stage of active multiple sclerosis lesions, as defined by Barnett and Prineas (2004).”
• Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS) (2011, background): “…majority of cases, although recent evidence suggests that initial damage to neuroglial elements can trigger secondary inflammation in some cases (Barnett and Prineas, 2004); (b) demyelination, the hallmark of MS, where the myelin sheath or the oligodendrocyte cell body is destroyed by the…”
• An updated histological classification system for multiple sclerosis lesions (2016, background): “Histopathological studies analyzing tissue samples from patients who died either shortly after a relapse or due to acute MS (so called Marburg’s type of MS) observed areas of microglial activation and dying oligodendrocytes [4], or microglia activation, edema, and low numbers of APP positive axons [”
• The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. (2006, background): “A recent study of very early MS lesions describes extensive apoptosis of oligodendrocytes as the earliest structural change observed (Barnett and Prineas , 2004).”
• The Immunopathology of Multiple Sclerosis: An Overview (2007, background): “Large concentric lesions, typical of Balo’s disease, are very rare, but small rims of concentric layering of myelinated and demyelinated tissue is seen in many active lesions of acute and relapsing MS, when they follow a demyelination pattern of hypoxia-like tissue injury as described above (9, 83).”