The Immunopathology of Multiple Sclerosis: An Overview

By Hans Lassmann, Wolfgang Brück, C. Lucchinetti. Brain Pathology, 2007

1,172 citations recorded by the source corpus.

Subfields: Neurology, Pathology and Forensic Medicine, Rheumatology

View Paper: https://www.semanticscholar.org/paper/0b7249a80347bfbdc2923672ab78f5035a7a312c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. Hans Lassmann
2. C. Lucchinetti
3. Wolfgang Brück
4. M. Schwartz
5. A. Prat

In Pathology and Forensic Medicine

1. Hans Lassmann
2. Wolfgang Brück
3. C. Lucchinetti
4. F. Aloisi
5. R. Ransohoff

In Rheumatology

1. Hans Lassmann
2. C. Lucchinetti
3. Wolfgang Brück

Citations in the corpus

• Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis (2019, background): “Multiple sclerosis is a chronic inflammatory disease of the central nervous system which leads to the formation of focal confluent lesions of primary demyelination in the white and gray matter and to diffuse damage and neurodegeneration in the entire brain (1).”
• Multiple Sclerosis Pathology. (2018, background): “The general pathology of MS has been described in detail in several recent reviews (Lassmann et al. 2007; Kutzelnigg and Lassmann 2014) and, therefore, this article focuses on some essential features.”
• Oxidative damage in multiple sclerosis lesions (2011, background): “Multiple sclerosis is a chronic inflammatory disease of the CNS, leading to focal plaques of primary demyelination with a variable degree of axonal and neuronal degeneration (Lassmann et al., 2007).”
• An updated histological classification system for multiple sclerosis lesions (2016, background): “Although there are a number of excellent reviews summarizing and discussing the histopathology of MS, for example [8, 14, 18, 31, 37, 46, 52], the focus of this article is to describe the most frequent lesion types and to provide guidelines for neuropathologists and researchers for the classificatio”
• Clinical and Pathological Insights into the Dynamic Nature of the White Matter Multiple Sclerosis Plaque (2015, background): “Although the fundamental features of the MS plaque have been characterized, criteria for the classification of subtypes are inconsistent and different schemes have been applied, particularly with respect to clinical correlation and underlying pathogenic mechanisms of disease.(2,4) Consequently, ther”
• Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. (2011, background): “…lesion formation and the number of infiltrating peripheral immune cells is decreased in the progressive phase of the disease and it is suggested that the immune response becomes largely confined to the CNS behind a relatively intact blood–brain barrier (Lassmann et al., 2007; Meinl et al., 2008).”
• BRAIN REGENERATION IN PHYSIOLOGY AND PATHOLOGY: THE IMMUNE SIGNATURE DRIVING THERAPEUTIC PLASTICITY OF NEURAL STEM CELLS (2011, background): “In these disorders, a close interplay between environmental factors and susceptibility genes (91, 120) triggers a cascade of events that engage the immune system, resulting in acute inflammatory injury of axons and glia, accompanied by frank demyelination (114, 119, 232).”