Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial.

By N. Lautenschlager, K. Cox, L. Flicker, J. Foster, F. V. van Bockxmeer, Jianguo Xiao, K. Greenop, O. Almeida. Journal of the American Medical Association (JAMA), 2008

1,672 citations recorded by the source corpus.

Subfields: Physical Therapy, Sports Therapy and Rehabilitation, Physiology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/57ce275d16532a4a1df832553cdc80e8945150a7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Physical Therapy, Sports Therapy and Rehabilitation

H. van Praag

In Physiology

In Psychiatry and Mental health

Citations in the corpus

Aerobic Exercise and Neurocognitive Performance: a Meta-Analytic Review of Randomized Controlled Trials (2010, methodology): “Continued Author/Year Sample Intervention Instruments Methodological Characteristics Hedge’s G Lautenschlager, 2008 (30) 170, elderly adults with MCI, age M 69 Duration: 72 wks¥ Frequency: 50 min, 3/wk Intensity: - - - Combined Strength Training: N MCI: Y Word list recall (immediate and delayed),…”
Exercise and the brain: something to chew on (2009, methodology): “However, in a 6 month intervention study there was an attenuated effect of exercise in ApoEε4 carriers that showed symptoms of memory decline [25].”
Physical activity in older age: perspectives for healthy ageing and frailty (2016, background): “In the nervous system, regular exercise helps to maintain cognitive function (Lautenschlager et al. 2008) and possibly also the numbers of peripheral motor neurons controlling leg muscles (Power et al. 2010, 2012) and overall improves balance and coordination to reduce risk of falls (Franco et al.…”
Muscles and their myokines (2011, background): “Physical activity during midlife appears to protect against dementia or cognitive decline and to improve cognitive performance in old adults with memory impairment (Rovio et al., 2005; Sun et al., 2010; Etgen et al., 2010a; Etgen et al., 2010b; Liu-Ambrose et al., 2010; Andel et al., 2008; Lautensch”
Systematic Review: Factors Associated With Risk for and Possible Prevention of Cognitive Decline in Later Life (2010, background): “A single RCT (173) with 170 participants examined an intervention of physical exercise and reported that at 18 months (12 months after treatment), the treatment group showed a decrease of 0.”
A Review of the Effects of Physical Activity and Exercise on Cognitive and Brain Functions in Older Adults (2013, background): “However, other studies have reported modest benefits [79] or no appreciable effect [80] of physical activity on cognition in patients with cognitive impairment.”
Exercise as medicine – evidence for prescribing exercise as therapy in 26 different chronic diseases (2015, background): “The effect was still present 1 year after cessation of exercise (Lautenschlager et al., 2008).”
Positive effect of acute mild exercise on executive function via arousal-related prefrontal activations: An fNIRS study (2014, background): “, 2008), but also lower the risks of age-related cognitive decline and neurological diseases later in life (Lautenschlager et al., 2008; Rovio et al., 2005; Verghese et al., 2003).”
The Risks of Ageism Model: How Ageism and Negative Attitudes toward Age Can Be a Barrier to Active Aging (2017, background): “Several studies suggest the benefits of being physically active, including reduced likelihood of chronic diseases (Berlin & Colditz, 1990), cognitive decline (Lautenschlager et al., 2008; Rovio et al., 2005), and mental health issues (Lawlor & Hopker, 2001; Netz, Wu, Becker, & Tenenhaum, 2005).”