Lipid landscapes and pipelines in membrane homeostasis

By J. Holthuis, A. Menon. Nature, 2014

796 citations recorded by the source corpus.

Subfields: Biochemistry, Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5736587755ed74488b6cb5f80f486cea250696fb

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In Molecular Biology

1. Doralicia Casares
2. C. A. Rosselló
3. P. Escribá

Citations in the corpus

• Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues (2019, background): “Phosphatidylcholine (PtdCho) and phosphatidylethanolamine (PtdEtn) heads are zwitterionic, whereas phosphatidylserine (PtdSer) and phosphatidylinositol (PtdIns) heads are anionic (reviewed in [16,17]).”
• Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles (2016, background): “Lipids are principal components of biomembranes and critical determinants of membrane properties such as intrinsic curvature, fluidity, and charge, and they play crucial roles in recruiting a wide variety of proteins to membranes (see e.g., [28] [29] [30] [31] for review).”
• Structural model of PORCN illuminates disease-associated variants and drug binding sites (2021, neutral): “Furthermore, DltB is on the bacterial plasma membrane while PORCN, ACAT1 and DGAT1 are located on the mammalian ER membrane, two membranes with very different compositions (Holthuis and Menon, 2014).”