Chemical remodelling of cell surfaces in living animals
By Jennifer A. Prescher, Danielle H. Dube, Carolyn R. Bertozzi. Nature, 2004
721 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/56bf366a650f0fe3b4bf716cddc6e527c73a1ab7
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- M. Finn
- Craig S Mckay
- Carolyn R. Bertozzi
- Jennifer A. Prescher
- Ralph Weissleder
- S. Hilderbrand
- D. Irvine
- Ellen M. Sletten
In Oncology
In Organic Chemistry
Citations in the corpus
- Therapeutic cell engineering using surface-conjugated synthetic nanoparticles (2010, background): “This strategy does not require cell preconditioning and complements traditional genetic engineering or chemical biology approache”
- Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation (2014, background): “…reagents prone to oxidation by air or metabolic enzymes, the Staudinger ligation is a popular choice for in vivo work due to its remarkable selectivity and compatibility with everything from cells (Agard et al., 2006; Chang et al., 2007; Saxon and Bertozzi, 2000) to animals (Prescher et al., 2004).”
- Click hydrogels, microgels and nanogels: emerging platforms for drug delivery and tissue engineering. (2014, background): “In the past years, several cyclooctyne molecules were found to react quickly with azides without a copper catalyst as a result of ring strain and electron-withdrawing fluorine substituents [47,48].”
- Chemistry in living systems (2005, background): “and tagging cell surface glycans in whole organism”
- Engineered antibody fragments and the rise of single domains (2005, background): “or from innovative in vivo chemical labeling strategies of tumor-specific surface glycan”
- Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging (2008, background): “To date, only a few bioorthogonal reactions have been reported, the most popular being the Staudinger ligation and the [3 + 2] cycloaddition “click” reaction between azides and alkynes (6,7).”