Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

By K. Schröder, S. Benkhoff, A. Mieth, R. Pliquett, J. Kosowski, Christoph Kruse, Peter Luedike, U. R. Michaelis, N. Weissmann, Stefanie Dimmeler and 2 more. Circulation Research, 2012

600 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/5540e57719c82167412ced444efa58887b00a4b1

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The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. M. Incalza
2. R. D'Oria
3. R. Brandes
4. C. Sena
5. A. Natalicchio
6. Sebastio Perrini
7. N. Weissmann
8. L. Laviola

Citations in the corpus

• Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases. (2018, background): “However, NOX4 could also exert protective rather than negative effects on the vasculature through the prevention of endothelial dysfunction under ischemic or inflammatory damage [46].”
• Endothelial dysfunction - a major mediator of diabetic vascular disease. (2013, background): “Apparently, under ischemia, hypertension or inflammatory stress Nox4derived H2O2 was suggested to have a protective role [112,113].”
• Nox family NADPH oxidases: Molecular mechanisms of activation. (2014, background): “deletion of Nox4 reduces the constitutive basal ROS formation of murine vessels [157] and kidneys [158].”